Homo machina is a video game in 2D, for smartphones and tablets, inspired by Dr. Fritz Kahn’s medical illustrations. Dive into a fantastic universe where the body becomes a gigantic mechanized factory, filled with tiny workers that are controlling every function of the human anatomy. Dr. Kahn, an infographics pioneer, excelled in scientific popularisation. His simplification of biology through the use of metaphors and analogies allowed everyone to understand the complex mechanics of the human body. By adapting his work into a video game, we want to share his vision that science can be fun and rise awareness about his iconic work.